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KMID : 0931320120120020103
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대한상부위장관.헬리코박터학회지
2012 Volume.12 No. 2 p.103 ~ p.107
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A Case of Steroid Dependent Eosinophilic Gastroenteritis Presenting as a Huge Gastric Ulcer
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Kim Yeon-Ji
Chung Woo-Chul
Kim Yae-Ni
Chung Yoon-Yung
Lee Kang-Moon
Paik Chang-Nyol
Chin Hyung-Min
Choi Hyun-Joo
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Abstract
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Eosinophilic gastroenteritis is defined as primary eosinophilic infiltration of the gastrointestinal tract. Endoscopic findings of this disease entity are non-specific, and huge gastric ulceration as initial presentation is extremely rare. We experienced a case of eosinophilic gastroenteritis presenting with abdominal pain in a 38 year-old-woman. Deep and huge ulceration in gastric antrum and body looked like advanced gastric cancer. Surgical resection was performed and histopathological examination showed dense infiltration of eosinophil without malignant cells. 5 years after surgery, diffuse abdominal pain and generalized edema developed and computed tomography showed entire wall thickening of the gastrointestinal tract. Random mucosal biopsy of the remnant stomach and terminal ileum showed mucosal eosinophilic infiltrations. She was treated with steroids and azathioprine but experienced frequent relapses and was dependent on steroids to maintain remissions. After 3 years, she died from infective endocarditis due to the prolonged use of immunosuppressive agents.
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KEYWORD
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Eosinophilic gastroenteritis, Gastric ulcer, Immunosuppressive agents
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